Technical Data
E2286-19
Endogenous Retrovirus Type K, Human, gag protein (HERV K)
Description:
Endogenous retroviruses contribute to the evolution of the host genome and can be associated with diseases in their hosts. Human endogenous retrovirus K (HERV-K) is related to mouse mammary tumor virus (MMTV) and is present in the genomes of catarrhines (humans, apes, and cercopithecoids (old world monkeys)). All humans have about 30 to 50 HERV-K proviruses in their germline DNA. Expression of HERV-K genes has been reported in several tissues including male germ cell tumors and normal placenta where budding viral particles can be detected.

Applications:
Suitable for use in ELISA and Western Blot. Other applications not tested.

Recommended Dilutions:
ELISA: 1:2000
Western Blot: 1:8000
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months aftere receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
MabIgG15i76Affinity Purified
SizeStorageShippingSourceHost
100ug-20CBlue IceMouse
Concentration:
~1mg/ml
Immunogen:
HERV K gag antigen (82kD).
Purity:
Purified by Protein G affinity chromatography.
Form
Supplied as a liquid in PBS, pH 7.4.
Specificity:
Recognizes human endogenous retrovirus type K (HERV K) gag and capsid antigens.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Toenjes, R.R. et. al. (1997) Virology 233: 280 - 291. 2. Barbulescu, M. et. al. (1999) Curr. Biol. 9: 861 - 868.