Technical Data
E3098-25A
Endothelin 1
Description:
Endothelins (ET) show potent constrictor activity in vascular and non-vascular smooth muscle. This family of 21-amino acid peptides exists in at least three isoforms, ET-1, ET-2, and ET-3, and is produced in endothelial and epithelial cells. ET's can mediate biological effects in cells and tissues, and have been shown to bind to an ET receptor in the lung, kidney, heart and liver.

Applications:
Suitable for use in Immunohistochemistry (frozen). Other applications not tested.

Recommended Dilution:
Optimal dilutions to be determined by the researcher.

Storage and Stability:
Lyophilized powder may be stored at 4°C for short-term only. Reconstitute to nominal volume by adding sterile 40-50% glycerol and store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
TypeIsotypeCloneGrade
PabSerum
SizeStorageShippingSourceHost
100ul-20°CBlue IceRabbit
Concentration:
Not determined
Immunogen:
Synthetic endothelin 1 covalently attached onto a carrier protein.
Purity:
Serum
Form
Supplied as a lyophilized powder. Reconstitution with 0.1ml of 10mg/ml BSA in PBS.
Specificity:
Recognizes Endothelin 1. Does not react to ACTH (human, 1-39), Calcitonin (human), Oxytocin and Vasoactive Intestinal Peptide. Cass specific for endothelin 1 and is suitable for use in immunohistochemical procedures.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.