Technical Data
E3351-04AP
Eotaxin (Blocking Peptide)
50ug
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Technical Data |
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E3351-04AP |
Eotaxin (Blocking Peptide) |
50ug |
| Growth Factors, Cytokines | Storage: -20°CShipping: Blue Ice |
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Peptide corresponding to amino acids 83 to 97 of human eotaxin (1,2). Chemokines play a key role in inflammation. The CC chemokine eotaxin is a potent and specific eosinophil chemoattractant that is expressed by a variety of cell types in certain inflammatory conditions (1,2). Some G-protein coupled chemokine receptors are also utilized as virus coreceptors for fusion and infection of cells. The eotaxin receptor CCR3 is required for HIV-1 entry into target cells such as microglia and eotaxin inhibits the infection of HIV-1 (3,4). |
Source: Synthetic peptide Purity: Purified 60-70% Concentration: 0.2mg/ml Form: Supplied as a lyophilized powder. Important Note: This product is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
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1. Kitaura M, Nakajima T, Imai T, et al., (1996) J Biol Chem 271:7725-30. 2. Ponath PD, Qin S, Ringler DJ, et al., (1996) J Clin Invest 97:604-12 3. He J, Chen Y, Farzan M, et al., (1997) Nature 385(6617):645-9. 4. Choe H, Farzan M, Sun Y, et al., (1996) Cell 85:1135-48.
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