Technical Data
Eotaxin (Blocking Peptide)
Molecular Biology Storage: -20CShipping: Blue Ice
Peptide corresponding to amino acids 83 to 97 of human eotaxin (1,2).
Chemokines play a key role in inflammation. The CC chemokine eotaxin is a potent and specific eosinophil chemoattractant that is expressed by a variety of cell types in certain inflammatory conditions (1,2). Some G-protein coupled chemokine receptors are also utilized as virus coreceptors for fusion and infection of cells. The eotaxin receptor CCR3 is required for HIV-1 entry into target cells such as microglia and eotaxin inhibits the infection of HIV-1 (3,4).
Source: Synthetic peptide
Purity: Purified 60-70%
Concentration: 0.2mg/ml
Form: Supplied as a lyophilized powder.

Important Note: This product is intended for research use only, not for use in human, therapeutic or diagnostic applications.
1. Kitaura M, Nakajima T, Imai T, et al., (1996) J Biol Chem 271:7725-30. 2. Ponath PD, Qin S, Ringler DJ, et al., (1996) J Clin Invest 97:604-12 3. He J, Chen Y, Farzan M, et al., (1997) Nature 385(6617):645-9. 4. Choe H, Farzan M, Sun Y, et al., (1996) Cell 85:1135-48.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.