Technical Data
E3351-04H
CCL11, aa24-97, Recombinant Human, His tag
100ug
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Technical Data |
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E3351-04H |
CCL11, aa24-97, Recombinant Human, His tag |
100ug |
| Growth Factors, Cytokines | Storage: -20°C/-70°CShipping: Blue Ice |
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CCL11 is a small cytokine belonging to the CC chemokine family that is also known as eotaxin-1. CCL11 selectively recruits eosinophils by inducing their chemotaxis, and therefore, is implicated in allergic responses. The effects of CCL11 are mediated by its binding to a G-protein-linked receptor known as a chemokine receptor. Chemokine receptors for which CCL11 is a ligand include CCR2, CCR3 and CCR5. Recombinant CCL11 protein was expressed in E. coli and purified by using conventional chromatography techniques. Source: Recombinant CCL11 protein was expressed in E. coli AA sequence: MGSSHHHHHH SSGLVPRGSH MGPASVPTTC CFNLANRKIP LQRLESYRRI TSGKCPQKAV IFKTKLAKDI CADPKKKWVQ DSMKYLDQKS PTPKP Storage and Stability: May be stored at 4°C for short-term only. For long-term storage, aliquot and store at -20°C. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. Molecular Weight: 10.6 kDa |
Source: E.coli Purity: ~90% (SDS-PAGE) Purified by immunoaffinity chromatography. Concentration: ~0.5mg/ml Form: Supplied as a liquid in PBS, pH 7.4, 10% glycerol. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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1.Imai T., et al. (1996) J Biol Chem. 271 (35): 21514–21 2.Kakinuma T,., et al. (2002) Cytokine. 20(1):1-6.
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