Technical Data
E3351-04H
CCL11, aa24-97, Recombinant Human, His-Tag
100ug
Growth Factors, Cytokines Storage: -20C/-70CShipping: Blue Ice
CCL11 is a small cytokine belonging to the CC chemokine family that is also known as eotaxin-1. CCL11 selectively recruits eosinophils by inducing their chemotaxis, and therefore, is implicated in allergic responses. The effects of CCL11 are mediated by its binding to a G-protein-linked receptor known as a chemokine receptor. Chemokine receptors for which CCL11 is a ligand include CCR2, CCR3 and CCR5. Recombinant CCL11 protein was expressed in E. coli and purified by using conventional chromatography techniques.

Source:
Recombinant CCL11 protein was expressed in E. coli

AA sequence:
MGSSHHHHHH SSGLVPRGSH MGPASVPTTC CFNLANRKIP LQRLESYRRI TSGKCPQKAV IFKTKLAKDI CADPKKKWVQ DSMKYLDQKS PTPKP

Storage and Stability:
May be stored at 4C for short-term only. For long-term storage, aliquot and store at -20C. Aliquots are stable for at least 6 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Molecular Weight:
10.6 kDa
Source: E.coli
Purity: ~90% (SDS-PAGE) Purified by immunoaffinity chromatography.
Concentration: ~0.5mg/ml
Form: Supplied as a liquid in PBS, pH 7.4, 10% glycerol.

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
1.Imai T., et al. (1996) J Biol Chem. 271 (35): 2151421
2.Kakinuma T,., et al. (2002) Cytokine. 20(1):1-6.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.