Technical Data
E3414-20B
Epithelial Membrane Antigen (EMA, CA15-3, Polymorphic Epithelial Mucin, PEM, Sialomucin or Episialin, MUC-1)
Description:
Epithelial Membrane Antigen, also referred to as EMA, CA15-3, Polymorphic Epithelial Mucin, PEM, Sialomucin or Episialin and MUC-1 is a glycoprotein of variable molecular weight, expressed by many glandular epithelial cells. Epithelia of breast, (acini and ducts), exocrine pancreas, bladder, gastrointestinal tracts, thyroid, endometrium and respiratory tract are generally EMA positive.

Applications:
Suitable for use in Immunohistochemistry. Other applications not tested.

Recommended Dilution:
Immunohistochemistry (formalin fixed paraffin embedded): 1:50-1:150
Immunohistochemistry: Frozen
Optimal dilutions to be determined by the researcher.

Positive Control:
Breast carcinoma

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
MabIgG111E183Purified
SizeStorageShippingSourceHost
500ul-20°CBlue IceHumanMouse
Concentration:
As reported
Immunogen:
Human milk fat globule membranes. Cellular Localization: Cell membrane and cytoplasmic.
Purity:
Purified
Form
Supplied as a liquid, 0.05% sodium azide.
Specificity:
Recognizes human EMA.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Heyderman et al. Br J Cancer 52: 355, 1985. 2. Cordell et al. Br J Cancer 52: 347, 1985. 3. Pinkus et al. Human Pathol 16: 929, 1985.