Technical Data
E3428-75A
Epothilone B
100ug
Biochemicals Storage: -20CShipping: Blue Ice
Epothilone B is a microtubule inhibitor isolated from the myxobacteria, Sorangium cellulosum. Like epothilone A, epothilone B acts by stabilising microtubule formation at the taxol binding site and causes cell cycle arrest at the G2/M transition, leading to cytotoxicity.

Source:
Epothilone B from Sorangium cellulosum.

Molecular Weight:
~507.7

Solubility:
Soluble in ethanol, methanol, DMF or DMSO. Poor water solubility.

Storage and Stability:
Lyophilized powder may be stored at -20C. Stable for 12 months at -20C. Reconstitute with DMSO. Aliquot to avoid repeated freezing and thawing. Store at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

CAS Number:
152044-54-7

Molecular Formula:
C27H41NO6S

Molecular Weight:
~507.7
Purity: ~98% (HPLC)
Concentration: Not determined
Form: Supplied as a white to off-white powder.

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. Toxicity and Hazards:All products should be handled by qualified personnel only, trained in laboratory procedures.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.