Technical Data
E3440-25A
Epstein Barr Virus, Early Antigen, Restricted p17, Bc12 (EA) (EBV)
Description:
The Early Restricted protein (EA-Restricted p17) of Epstein-Bar Virus is encoded by the viral BHFR1 gene. EA-Restricted p17 is a 17kD protein (p17) with protein kinase activity. EA-Restricted p17 is a functional homologue of the anti-apoptotic oncoprotein bcl-2, which is expressed during the switch from latency to lytic replication and may be involved in proliferation of EBV infected cells. However, EA-Restricted p17 does not appear to be essential for virus replication or transformation of B cells in vitro.

Applications:
Suitable for use in ELISA, Western Blot, Immunofluorescence and Immunoprecipitation. Other applications not tested.

Recommended Dilutions:
Optimal dilutions to be determined by researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
MabIgG2a2Q1912Purified
SizeStorageShippingSourceHost
100ug-20CBlue IceMouse
Concentration:
~1mg/ml
Immunogen:
Epstein Barr Virus, Early Antigen
Purity:
Purified
Form
Supplied as a liquid in PBS, pH 7.2, 0.1% sodium azide.
Specificity:
Recognizes Epstein Barr Virus, Early Antigen, Restricted p17, Bc12 homologue at ~17kD. Species Crossreactivity: human
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Nicholls, J. et al., (2001) J Med Virol 65:105-113. 2. Meseda, C. et al., (2000) J Gen Virol 81:1801-1805. 3. Dawson, C. et al., (1998) J Virol 72:9016-9024. 4. Pearson, G. et al., (1987) Virol 160:151-161.