		Technical Data
E9100-03B	Ezrin (Cytovillin 2, Cytovillin, CVIL, CVL, DKFZp762H157, FLJ26216, MGC1584, p81, Villin 2, Villin-2, VIL2)

Description:
The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. It plays a key role in cell surface structure adhesion, migration, and organization.

Applications:
Suitable for use in ELISA and Western Blot. Other applications not tested.

Recommended Dilution:
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20°C. Aliquots are stable for at least 3 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Type	Isotype	Clone	Grade
Pab	IgG		Affinity Purified

Size		Storage	Shipping	Source	Host
100ug		-20°C	Blue Ice	Human	Goat

Concentration:

~0.5mg/ml

Immunogen:

Synthetic peptide, C-QDYEEKTKKAER, representing the internal region of the human protein according to NP_003370.2. Homology: Dog

Purity:

Purified by immunoaffinity chromatography.

Form

Supplied as a liquid in Tris-saline, pH7.2, 0.5% BSA.

Specificity:

Species Crossreactivity: Human.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

Stanasila L, Abuin L, Diviani D, Cotecchia S. , Ezrin directly interacts with the alpha1b-adrenergic receptor and plays a role in receptor recycling. ,J Biol Chem. 2006 Feb 17;281(7):4354-63. Epub 2005 Dec 13. , PMID: 16352594