Technical Data
Ezrin (Radixin, Moesin, Cytovillin, p81, Membrane-organizing extension spike protein)
Human moesin (membrane-organizing extension spike protein), a member of the ezrin, radixin, moesin (ERM) protein family, which acts as a linker protein between the plasma membrane
and the actin cytoskeleton, and as a signal transducer in responses involving cytoskeletal remodelling. Moesin is localized to cytoplasmic projections (filopodia) which extend from the leading edge of migrating cells, which play a key role in cell movement, signaling and cell-cell recognition.

Suitable for use in ELISA and Western Blot. Other applications not tested.

Recommended Dilution:
ELISA: 1:16000
Western Blot: 1.0-3.0ug/ml, detects a band of ~70kD in human spleen cell lysates.
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20C. Aliquots are stable for at least 12 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
PabIgGAffinity Purified
100ug-20CBlue IceHumanGoat
Peptide sequence C-NARDESKKTAND from the internal region of moesin (NP_002435.1).
Purified by affinity chromatography.
Supplied as a liquid in TBS, pH 7.2, 0.02% sodium azide, 0.5% BSA.
Recognizes human moesin.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Tsukita, S. et al. (1997) Cell Biol. 9:70-75.