Description:
Application(s): Flow Cytometry Immunocytochemistry Immunohistochemistry (frozen sections, paraffin sections) Recommended working dilutions are 1:200-1:1000.
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| Type | Isotype | Clone | Grade |
| Mab | IgG3 | 6D52 | Highly Purified |
|
| Size | | Storage | Shipping | Source | Host |
| 100ug | | 4°C | Blue Ice | Human | Mouse |
|
| Concentration: |
| 1mg/ml |
| Immunogen: |
| Mouse L cells stably overexpressing human Fas (CD95; APO-1). |
| Purity: |
| Purified from concentrated hybridoma tissue culture supernatant.95% (SDS-PAGE). |
| Form |
| Liquid. Purified antibody in PBS. |
| Specificity: |
| Recognizes human Fas. |
|
| Intended for research use only. Not for use in human, therapeutic, or diagnostic applications. |
1. Differential regulation and ATP requirement for caspase-8 and caspase-3 activation during CD95- and anticancer drug-induced apoptosis: D. Ferrari, et al.; J. Exp. Med. 188: 979 (1998). 2. Anticancer drugs induce caspase-8/FLICE activation and apoptosis in the absence of CD95 receptor/ligand interaction: S. Wesselborg, et al.; Blood 93: 3053 (1999). 3. IL-10 induces apoptosis in human monocytes involving the CD95 receptor/ligand pathway: M. Schmidt, et al.; Eur. J. Immunol. 30: 1769 (2000). |
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