Technical Data
F0019-90B
Fatty Acid Binding Protein 7, Brain (FABP7, B-FABP, Brain Lipid Binding Protein, BLBP, DKFZp547J2313, FABPB, MRG)
Description:
The FABP family is a group of small highly conserved cytoplasmic proteins that bind long chain fatty acids and other hydrophobic ligands. Research suggests that FABPs are involved in fatty acid uptake, transport and metabolism.

FABP7 is expressed in the brain and other neurological tissues. FABP7 is an important component in the establishment of the radial glial fiber system in the developing brain, a system that is required for the migration of immature neurones to establish cortical layers.

Studies have also demonstrated that FABP7 is frequently expressed in melanomas.

Applications:
Suitable for use in Western Blot. Other applications not tested.

Recommended Dilution:
Western Blot: 0.5-1ug/ml
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20C. Aliquots are stable for at least 12 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
100ugBlue IceHumanRabbit
Concentration:
~1mg/ml
Immunogen:
A 17 amino acid peptide located near the center of human FABP7.
Purity:
Purified by immunoaffinity chromatography.
Form
Supplied as a liquid in PBS, 0.02% sodium azide.
Specificity:
Recognizes human FABP7.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Goto, Y., et al. (2006) A new melanoma antigen fatty acid-binding protein 7, involved in proliferation and invasion, is a potential target for immunotherapy and molecular target therapy. Cancer Res.; 66:4443-9. 2. Chmurzynska, A. (2006) The multigene family of fatty acid-binding proteins (FABPs): function, structure and polymorphism. J. Appl. Genet.; 47:39-48. 3. Arai, Y., et al. (2005) Role of FABP7, a downstream gene of pax6, in the maintenance of neuroepithelial cells during early embryonic development of the rat cortex. J. Neurosci.; 25:9752-61. 4. Shimizu, F., et al. (1997) Isolation and expression of a cDNA for human brain fatty acid-binding protein (B-FABP). Biochim. Biophys. Acta; 1354:24-28.