Technical Data
F0023-87
FBXO6 (F-box Only Protein 6, F-Box/G-domain Protein 2, FBG 2, FBG2, FBX 6, FBX6)
Description:
FBXO6 (F Box G Domain Protein 2, F Box Only Protein 6, FBG 2, FBG2, FBX 6, FBX6, FBXO 6) is directed against targets that have limited or no commercial antibodies available to them and for which there are no data on the expression of the protein in the range of common cell lines and tissues. These antibodies are affinity purified using their peptide immunogen and are known to give low background staining in a western blot. However no additional claims are made for their ability to recognize native protein in any application.

The F box, named after cyclin F in which it was originally observed, is an approximately 40-amino acid motif that binds SKP1. F-box proteins are components of modular E3 ubiquitin protein ligases called SCFs (SKP1, cullin, F-box proteins), which function in phosphorylation-dependent ubiquitination.

Applications:
Suitable for use in ELISA. Other applications not tested.

Recommended Dilution:
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20C. Aliquots are stable for at least 12 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
100ug-20CBlue IceHumanGoat
Concentration:
~0.5mg/ml
Immunogen:
Synthetic peptide corresponding to aa280-293, EAAQSPYRAVVQIF from the C-Terminus of human FBXO6 (NP_060908).
Purity:
Purified by immunoaffinity chromatography.
Form
Supplied as a liquid in TBS, pH 7.2, 0.5% BSA.
Specificity:
Recognizes human FBX06.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
Ilyin GP et al. A new subfamily of structurally related human F-box proteins. Gene 296:11-20 (2002).