Technical Data
F4015-04Y2
FTH1, CT (Ferritin Heavy Chain, Ferritin H Subunit, Cell Proliferation-inducing Gene 15 Protein, PIG15, OK/SW-cl.84, FTHL6, FTH)
Description:
FRIH is the heavy subunit of ferritin, the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in ferritin proteins are associated with several neurodegenerative diseases.

Applications:
Suitable for use in ELISA and Western Blot. Other applications not tested.

Recommended Dilution:
ELISA: 1:1,000
Western Blot: 1:50-1:100
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
100ug-20°CBlue IceHumanRabbit
Concentration:
~0.25mg/ml
Immunogen:
Synthetic peptide selected from the C-terminal region of human FRIH (KLH).
Purity:
Purified by immunoaffinity chromatography.
Form
Supplied as a liquid in PBS, 0.09% sodium azide.
Specificity:
Recognizes human FRIH.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Coffman,L.G., Proc. Natl. Acad. Sci. USA 106(2), 570-575 (2009). 2. Sammarco,M.C., J. Biol. Chem. 283(8), 4578-4587 (2008).