Technical Data
F4203-02F
Fibrinogen (Coagulation Factor I)
Description:
Fibrinogen is a 340kD glycoprotein which plays an important role in the coagulation process. Fibrinogen activation is also involved in cellular and matrix interactions, the inflammatory response, cardiovascular disease and neoplasia.

Applications:
Suitable for use in ELISA, Immunofluorescence, and Immunohistochemistry. Other applications not tested.

Recommended Dilutions:
ELISA: 1:50-1:100
Immunofluorescence: 1:200-1:400
Immunohistochemistry: Frozen sections
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. 
TypeIsotypeCloneGrade
PabIgGHighly Purified
SizeStorageShippingSourceHost
1ml-20°CBlue IceHumanSheep
Concentration:
~5mg/ml
Immunogen:
Human fibrinogen purified from plasma.
Purity:
Purified by ion exchange chromatography.
Form
Supplied as a liquid in PBS, pH 7.4, 0.09% sodium azide.
Specificity:
Recognizes human fibrinogen. Displays minimal crossreactivity with related serum proteins. Species Crossreactivity: mouse and rat.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Kamath, S. and Lip, G.Y. (2003) Fibrinogen: biochemistry, epidemiology and determinants. Q.J.M. 96: 711-729. 2. Mosesson, M.W. (2005) Fibrinogen and fibrin structure and functions. J. Thromb. Haemost. 3: 1894-1904. 3. Brill, A. et al. (2011) von Willebrand factor-mediated platelet adhesion is critical for deep vein thrombosis in mouse models. Blood. 117: 1400-7.