Technical Data
F4208-50
Fibroblast Activation Protein (FAP)
Description:
Fibroblast Activation Protein (FAP) is a cell surface glycoprotein of reactive human fibroblasts. Among the normal adult organs tested, F4208-50 does not show immunoreactivity in immunohistological studies with either resting fibroblasts (fibrocytes) of the normal origin mesenchyme or the parenchymal cells. The single exception noted is a subset of endocrine cells in the pancreatic islets, presumably glucagon-producing A cells.

Applications:
Suitable for use in Flow Cytometry, Immunoprecipitation and Immunohistochemistry. Other applications not tested.

Recommended Dilution:
Immunohistochemistry: Stains unfixed, acetone-fixed or ethanol-fixed frozen sections. Acetone-fixed frozed sections yield optimal staining results. Not suitable for paraffin sections.
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
MabIgG16D394Affinity Purified
SizeStorageShippingSourceHost
100ug-20CBlue IceHumanMouse
Concentration:
~1mg/ml
Immunogen:
Human Fibroblast Activation Protein.
Purity:
Purified by Protein A affinity chromatography.
Form
Supplied as a liquid in PBS.
Specificity:
Recognizes human Fibroblast Activation Protein. Crossreacts with a subset of endocrine cells in the pancreatic islets, presumably glucagon-producing A cells.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.