Technical Data
F4210-01C
FGF1, Recombinant, Mouse, aa16-155, His-tag (Heparin-binding Growth Factor 1, HBGF-1, Acidic Fibroblast Growth Factor, aFGF, Beta-endothelial Cell Growth Factor, ECGF-beta, FGFA)
100ug
500ug
Growth Factors, Cytokines Storage: -20CShipping: Blue Ice
FGF1, belongs to the fibroblast growth factor family. It is a potent mitogenic agent. FGF1 has been detected in large amounts in the brain. Other cells known to express FGF1 include hepatocytes, vascular smooth muscle cells, CNS neurons, skeletal muscle cells, fibroblasts, keratinocytes, endothelial cells, intestinal columnar epithelium cells and pituitary basophils and acidophils. The growth factor acts through activation of specific cell-surface receptors leading to intracellular tyrosine phosphorylation cascade.

Source:
Recombinant corresponding to aa16-155 from mouse FGF1, fused to His-tag at N-terminal expressed in E.coli.

AA Sequence:
MGSSHHHHHH SSGLVPRGSH MFNLPLGNYK KPKLLYCSNG GHFLRILPDG TVDGTRDRSD QHIQLQLSAE SAGEVYIKGT ETGQYLAMDT EGLLYGSQTP NEECLFLERL EENHYNTYTS KKHAEKNWFV GLKKNGSCKR GPRTHYGQKA ILFLPLPVSS D

Molecular Weight:
~18kD (MALDI-TOF)

Endotoxin: ~1EU/ug

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Molecular Weight:
~18kD
Source: E.coli
Purity: ~90% (SDS-PAGE)
Concentration: ~1mg/ml
Form: Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, 1mM DTT, 30% glycerol, 0.1M sodium chloride.

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
1. Jaye M., et al. (1986) Science. 233:541-544. 2. Stauber D J., et al. (2000) Proc Natl Acad Sci. 97:49-54.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.