Technical Data
Fibroblast Growth Factor 4, Recombinant, Human (FGF-4, Heparin Secretory Transforming Protein 1, HSTF-1, HST-1, HST, Transforming Protein KS3, Heparin-binding Growth Factor 4, HBGF-4, HSTF1, KS3)
Molecular Biology Storage: -20CShipping: Blue Ice
FGF4 is a heparin binding growth factor that is a member of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF4 signals through the FGFR1c, 2c, 3c, and 4. Recombinant human FGF4 is a 19.7kD protein consisting of 182 amino acids.

Biological Activity:
The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF-receptors is 0.5ng/ml, corresponding to a speci c activity of
2x10e6 units/mg.

Storage and Stability:
Lyophilized powder may be stored at -20C. Stable for 12 months at -20C. Reconstitute with PBS, 0.1% HSA or BSA, aliquot and store at -20C. Reconstituted product is stable for 3 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Country of Origin:

Molecular Weight:
Source: Recombinant, human (E. coli)
Purity: 95% by SDS-PAGE and HPLC. Endotoxin: 0.1ng/ug (1EU/ug).
Form: Supplied as a lyophilized powder from 10mM sodium phopshate, pH 7.4, 100mM sodium chloride.
Reconstitution: Reconstitute in sterile ddH2O to 0.1-1mg/ml. This solution can be diluted into other aqueous buffers.

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.