Technical Data
F4211-50
Fibroblast Growth Factor 8, Recombinant, Human (FGF8)
5ug
25ug
25ug
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Technical Data |
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F4211-50 |
Fibroblast Growth Factor 8, Recombinant, Human (FGF8) |
5ug 25ug |
| Growth Factors, Cytokines | Storage: -20°CShipping: Blue Ice |
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Fibroblast Growth Factor-8 (FGF-8b) is a heparin binding growth factor belonging to the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. There are 4 known alternate spliced forms of FGF8: FGF8A, FGF-8B, FGF-8E and FGF-8F. The human and murine FGF8 A and B are identical. Human and murine FGF8 E and F are 98% identical. FGF-8 targets mammary carcinoma cells and other cells expressing the FGF receptors. Recombinant human FGF-8b is a 22.4kD protein consisting of 193 amino acid residues. Storage and Stability: Lyophilized powder may be stored at -20°C . Reconstitute with 10mM Tris, pH 8.0, 75mM sodium chloride, aliquot and store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. Country of Origin: USA Molecular Weight: 22.4kD |
Source: Recombinant, Human (E. coli) Purity: 95% by SDS-PAGE and HPLC. Endotoxin: 0.1ng/ug (1EU/ug). Form: Supplied as a lyophilized powder from 10mM Tris, pH 8.0, 75mM sodium chloride. Reconstitute in 10 mM Tris, pH 8.0. Specificity: Biological Activity: The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF-receptors is 0.5ng/ml, corresponding to a speci c activity of 2 x 10e6u/mg Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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