Technical Data
Fibroblast Growth Factor 17, Recombinant, Human (FGF17)
Molecular Biology Storage: -20CShipping: RT
Recombinant corresponding to 195aa from human Fibroblast Growth Factor 17 expressed in E. coli.

Molecular Weight:

Endotoxin: ~0.1ng/ug

Biological Activity:
ED50 <0.5ng/ml (>2x106units/mg), determined by the dose dependent stimulation of thymidine uptake by BaF3 cells expressing FGF-receptors. FGF-17 is a heparin binding growth factor that is involved in controlling tissue growth and morphogenesis. It has been found in the embryo at the midbrain-hindbrain junction, in telencephalondiencephalon transition, in the smooth muscle of major artery walls, in chondrocytes, osteoblast precursors and in mesenchymal cells.

Storage and Stability:
Lyophilized powder may be stored at -20C. Stable for 12 months at -20C. Reconstitute with sterile buffer. Aliquot to avoid repeated freezing and thawing. Store at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Molecular Weight:
Purity: ~95% (SDS-PAGE, HPLC)
Concentration: Not determined
Form: Supplied as a lyophilized powder in 10mM Tris, pH 7.4, with 30mM sodium chloride. Reconstitute with 5mM Tris, pH 8.0, to 0.1-1.0 mg/ml.

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
1. Xu, J. et al. (1999) Mech. Dev. 83:165.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.