Technical Data
F4212-90
Fibroblast Growth Factor 18, Recombinant, Human (FGF18)
5ug
25ug
Growth Factors, Cytokines Storage: -20CShipping: Blue Ice
The FGFs play key roles in controlling tissue growth, morphogenesis and repair in animals. FGF-18 is a newly discovered heparin binding growth factor that stimulates the proliferation and activation of cells that express FGF receptors. Recombinant Human FGF-18 is a 21.2kD protein containing 182aa.

Biological Activity:
The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF-receptors is 0.5ng/ml, corresponding to a speci c activity of
2x10e6 units/mg.

Storage and Stability:
Lyophilized powder may be stored at 4C for short-term only. Reconstitute to nominal volume by adding sterile 5mM Tris and store at -20C. Reconstituted product is stable for 12 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.e made in assay buffer.

Country of Origin: USA

Molecular Weight:
21.2kD
Source: Human, recombinant protein expressed in E. coli
Purity: 95% by SDS-PAGE and HPLC. Endotoxin: 0.1ng/ug (1EU/ug).
Form: Supplied as a lyophilized powder from 10mM Tris, pH 8.0.
Reconstitute in 5mM Tris, pH 8.0 to a concentration of 0.1-1mg/ml. Further dilutions should be made in aqueous buffers supplemented with carrier protein, such as 0.1-1% BSA.

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
1. J Biol Chem. 2004 Jun 25;279(26):27743-52. Epub 2004 Apr 08. 2. J Biol Chem. 2004 Mar 26;279(13):12346-54. Epub 2004 Jan 05. 3. J Cereb Blood Flow Metab. 2004 Jan;24(1):114-23. 4. J Biol Chem. 2004 Mar 12;279(11):9765-76. Epub 2003 Dec 29. 5. Development. 2003 Dec;130(25):6175-85. Epub 2003 Nov 05. 6. Cancer Res. 2003 Oct 1;63(19):6116-20 7. Stroke. 2003 Jun;34(6):1507-12. 8.Epub 2003 May 08. 9. Dev Dyn. 2003 Apr;226(4):663-74. 10. Proc Natl Acad Sci U S A. 2002 Dec 10;99(25):16279-84. 11. Epub 2002 Dec 02.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.