Technical Data
F4212-94B
Fibroblast Growth Factor 22, Recombinant, Human (FGF22)
5ug
20ug
100ug
Growth Factors, Cytokines Storage: -70CShipping: Blue Ice
Fibroblast growth factor 22, a protein which in humans is encoded by the FGF22 gene, is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth,morphogenesis, tissue repair, tumor growth and invasion. The mouse homolog of this gene was found to be preferentially expressed in the inner root sheath of the hair follicle, which suggested a role in hair development.

Recombinant Human FGF-22 produced in E. coli is a single, non-glycosylated polypeptide chain containing 148 amino acids and having a molecular mass of 17173D.

Biological Activity: Measured in a cell proliferation assay using IEC6 cell line (20ng/ml can stimulate the cell proliferation of IEC6 cell line.

AA Sequence:
The sequence of the first five N-terminal amino acids was determined and was found to be
Thr-Pro-Ser-Ala-Ser.

Storage and Stability:
Lyophilized powder may be stored at -20C. Stable for 12 months at -20C. Reconstitute with sterile ddH2O, aliquot and store at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Molecular Weight:
17.2kD
Source: Recombinant, human, E. coli
Purity: 95% as determined by RP-HPLC; Reducing and non-reducing SDS-PAGE.
Form: Supplied as a lyophilized powder. Reconstitute with sterile dH2O PBS to 0.1-1mg/ml, which can be further diluted into other aqueous solutions.

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.