Suitable for use in ELISA and Immunohistochemistry. Other applications not tested.
Immunohistochemistry: Frozen sections.
Optimal dilutions to be determined by the researcher.
Storage and Stability:
May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
|100ug||4°C (-20°C Glycerol)||Blue Ice||Human||Mouse|
|T-cell lymphoma biopsy|
|Purified by affinity chromatography.|
|Supplied as a liquid in PBS, pH 7.2, 50% glycerol, 0.1% sodium azide, 0.1% BSA.|
|Reacts with fibronectin in connectie tissues and vessels. Strongly stains matrix fibronectin in tissues. Animal biodistribution experiments have shown that after intravenous administration, F4215-04A localizes to tumor vessels where it binds to the underlying basement membrane. At the same time, the antigen recognized by F4215-04A is not accessible in normal tissues to circulating antibody indicating that this antibody can be used to target tumor vessels specifically in vivo. Does not recognize a soluble dimeric form of fibronectin (plasma fibronectin). Species Crossreactivity: Human and mouse.|
|Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.|
1. Epstein, A.L., et al., Cancer Research 55(12): 2673-80 (1995).|