Description:
Applications:
Suitable for use in ELISA and Immunohistochemistry. Other applications not tested.
Recommended Dilution:
Immunohistochemistry: Frozen sections.
Optimal dilutions to be determined by the researcher.
Storage and Stability:
May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
|
| Type | Isotype | Clone | Grade |
|---|
| Mab | IgG1 | 4i21 | Affinity Purified |
|
| Size | | Storage | Shipping | Source | Host |
|---|
| 100ug | | 4°C (-20°C Glycerol) | Blue Ice | Human | Mouse |
|
| Concentration: |
| ~0.2mg/ml |
| Immunogen: |
| T-cell lymphoma biopsy |
| Purity: |
| Purified by affinity chromatography. |
| Form |
| Supplied as a liquid in PBS, pH 7.2, 50% glycerol, 0.1% sodium azide, 0.1% BSA. |
| Specificity: |
| Reacts with fibronectin in connectie tissues and vessels. Strongly stains matrix fibronectin in tissues. Animal biodistribution experiments have shown that after intravenous administration, F4215-04A localizes to tumor vessels where it binds to the underlying basement membrane. At the same time, the antigen recognized by F4215-04A is not accessible in normal tissues to circulating antibody indicating that this antibody can be used to target tumor vessels specifically in vivo. Does not recognize a soluble dimeric form of fibronectin (plasma fibronectin). Species Crossreactivity: Human and mouse. |
|
| Intended for research use only. Not for use in human, therapeutic, or diagnostic applications. |
1. Epstein, A.L., et al., Cancer Research 55(12): 2673-80 (1995).
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