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Technical Data |
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F6069-95D |
Chemokine (C-X3-C Motif) Ligand 1, Recombinant Human (CX3CL1, A-152E5.2, ABCD-3, C3Xkine, CX3C Membrane-anchored Chemokine, C-X3-C Motif Chemokine 1, CXC3, CXC3C, FKN, Fractalkine, Fractalkine, Neurotactin, Neurotactin, NTN, NTT, SCYD1, Small-inducible Cy |
100ug |
| Growth Factors, Cytokines | Storage: -20°CShipping: Blue Ice |
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CX3CL1, also known as fractalkine. CX3CL1 has a unique CX3C cysteine motif near the amino terminus and is the first member of a fourth branch of the chemokine superfamily. Unlike other known chemokines, CX3CL1 is a type 1 membrane protein containing a chemokine domain tethered on a long mucin like stalk. It is expressed in a membrane-bound form on activated endothelial cells and mediates attachment and firm adhesion of T cells, monocytes and NK cells. Also, CX3CL1 elicits its adhesive and migratory functions by interacting with the chemokine receptor CX3CR1. Recombinant human CX3CL1, fused to His-tag at N-terminus, , expressed in E. coli and purified by using conventional chromatography techniques. Source: Recombinant human CX3CL1/Fractalkine, aa25- 100, His-tagged, expressed in E. coli AA Sequence: MGSSHHHHHH SSGLVPRGSH MQHHGVTKCN ITCSKMTSKI PVALLIHYQQ NQASCGKRAI ILETRQHRLF CADPKEQWVK DAMQHLDRQA Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. For long-term storage, aliquot and store at -20°C. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. Molecular Weight: 10.9kD |
Source: E.coli Purity: ~90% by SDS-PAGE Purified by immunoaffinity chromatography. Form: Supplied as liquid in Phosphate buffered saline, pH7.4, 10% glycerol Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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