Technical Data
Fractalkine, Recombinant, Human (Chemokine, CX3C Motif, Ligand 1, CX3CL1, Small Inducible Cytokine Subfamily D, Member 1, SCYD1, Neurotactin, NTT, NTN)
Molecular Biology Storage: -20CShipping: Blue Ice
Fractalkine is a large cytokine protein containing multiple domains and is the only known member of the CX3C chemokine family. Fractalkine is produced as a long protein (with 373aa in humans) with an extended mucin-like stalk and a chemokine domain on top. The mucin-like stalk permits it to bind to the surface of certain cells. Fractalkine elicits its adhesive and migratory functions by interacting with the chemokine receptor CX3CR1.

Recombinant corresponding to aa25-100 from human Fractalkine, fused to 6x His-tag at N-terminal, expressed in E. coli.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Source: E. coli
Purity: ~95% (SDS-PAGE)
Concentration: As reported
Form: Supplied as liquid.

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
1. Pan, Y. et al. (1997) Nature 387: 611-617. 2. Bazan, J.F. et al. (1997) Nature 385: 640-644.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.