		Technical Data
F6072-60C	Fragilis (Interferon-induced Transmembrane Protein 3, Interferon-inducible Protein 1-8U, IFITM3)

Description:
Fragilis (IFITM3) is a 133aa protein belonging to the CD225 family and contains an N-terminal signal sequence, three potential phosphorylation sites and a C-terminal leucine zipper. It plays a role in cell adhesion and cell differentiation. It behaves as a homing signal, enabling the cells localization. IFITM3 protein is approximately 90% identical to IFITM2. The guidance activities of IFITM1 and IFITM3 were mediated by their unique N-terminal domains. It is expressed on the surface of primordial germ cells

Applications:
Suitable for use in ELISA. Other applications not tested.

Recommended Dilution:
ELISA: 1:100-1:1000
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Type	Isotype	Clone	Grade
Pab	IgG		Serum

Size		Storage	Shipping	Source	Host
100ul		-20°C	Blue Ice	Mouse	Rabbit

Concentration:

Not determined.

Immunogen:

Synthetic peptide corresponding to aa47-58 (NMPREVSVPDHV) of mouse Fragilis.

Purity:

Serum

Form

Supplied as a liquid, 0.025% sodium azide, 50% glycerol.

Specificity:

Recognizes mouse Fragilis. Species Crossreactivity: rat. Species sequence homology: bovine.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

1. Lewin, AR. et al. Eur. J. Biochem. 199:417-423 (1991). 2. Tanaka, SS. et al. Dev. Cell. 9:745-756 (2005).