Technical Data
F6072-60C
Fragilis (Interferon-induced Transmembrane Protein 3, Interferon-inducible Protein 1-8U, IFITM3)
Description:
Fragilis (IFITM3) is a 133aa protein belonging to the CD225 family and contains an N-terminal signal sequence, three potential phosphorylation sites and a C-terminal leucine zipper. It plays a role in cell adhesion and cell differentiation. It behaves as a homing signal, enabling the cells localization. IFITM3 protein is approximately 90% identical to IFITM2. The guidance activities of IFITM1 and IFITM3 were mediated by their unique N-terminal domains. It is expressed on the surface of primordial germ cells

Applications:
Suitable for use in ELISA. Other applications not tested.

Recommended Dilution:
ELISA: 1:100-1:1000
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGSerum
SizeStorageShippingSourceHost
100ul-20CBlue IceMouseRabbit
Concentration:
Not determined.
Immunogen:
Synthetic peptide corresponding to aa47-58 (NMPREVSVPDHV) of mouse Fragilis.
Purity:
Serum
Form
Supplied as a liquid, 0.025% sodium azide, 50% glycerol.
Specificity:
Recognizes mouse Fragilis. Species Crossreactivity: rat. Species sequence homology: bovine.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Lewin, AR. et al. Eur. J. Biochem. 199:417-423 (1991). 2. Tanaka, SS. et al. Dev. Cell. 9:745-756 (2005).