Technical Data
F6401-12A
FZD3 (Frizzled 3, Frizzled-3, Fz-3, hFz3)
Description:
Frizzled-3 (FZD3) is a Frizzled Receptor that mediates Wnt signaling. It is widely expressed, mostly in brain and urogenital tissues. FZD3 is also expressed in the epidermis and developing hair follicles. FZD3 has been implicated in the development of axon tracts in the forebrain. A truncated form of FZD3 exists due to alternative splicing. FZD3 expression has been documented in blood, brain, colon, kidney, lung, lymph node, ovary, pancreas, skeletal muscle, skin, spinal cord, stomach, urogenital tract, and uterus. ESTs have been isolated from amnion, brain, colon, eye, heart, kidney, lymph, skin, and testis libraries.

Applications:
Suitable for use in ELISA. Other applications not tested.

Recommended Dilution:
ELISA: 1:2000
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabAffinity Purified
SizeStorageShippingSourceHost
100ug-20CBlue IceHumanGoat
Concentration:
~0.5mg/ml
Immunogen:
Synthetic peptide corresponding to C-DDQRSKAGSIHSK, from FZD3, at the internal region of the protein (NP_059108.1).
Purity:
Purified by immunoaffinity chromatography.
Form
Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
Specificity:
Recognizes FZD3. Species sequence homology: Human, mouse and rat.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. You J, Nguyen AV, Albers CG, Lin F, Holcombe RF. Wnt Pathway-Related Gene Expression in Inflammatory Bowel Disease. Dig Dis Sci. 2007 Oct 16.