Technical Data
F6401-38C
FZD8 (Frizzled 8, Frizzled-8, Fz-8, hFz8)
Description:
Frizzled 8 is one of the mammalian homologs of the Drosophila frizzled proteins, which are known to interact with Wnt proteins (1 and 2). Frizzled 8, originally isolated from a human fetal cDNA library, is also known also asFZD8 or FZ8.

Applications:
Suitable for use in ELISA. Other applications not tested.

Recommended Dilution:
ELISA: 1:100-1:1000
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
100ug-20CBlue IceHumanRabbit
Concentration:
~0.5mg/ml
Immunogen:
Synthetic peptide corresponding to aa569-584 of human FZD8 (CLRDLQPDQARRPDYA); (Genbank accession no. NP_114072.)
Purity:
Purified by Protein G affinity chromatography.
Form
Supplied as a liquid, 0.2% gelatin, 0.05% sodium azide.
Specificity:
Recognizes human FZD8. Species sequence homology: mouse and rat.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Terasaki H, Saitoh T, Shiokawa K, and Katoh M. 2002. M Frizzled-10, up-regulated in primary colorectal cancer, is a positive regulator of the WNT-beta-catenin-TCF signaling pathway. Int J Mol Med. 9:107-112. 2. Saitoh T, Hirai M, and Katoh M. 2001. Molecular cloning and characterization of human Frizzled-8 gene on chromosome 10p11.2. Int J Oncol. 5:991-996.