Technical Data
F9005-05
(S) FTY720 Phosphate (2-(S)-Amino-2-[2-(4-octylphenyl)ethyl]-1,3-propanediol Mono(dihydrogen phosphate) Ester, (S)-FTY720-P)
1mg
Biochemicals Storage: -20CShipping: RT
A sphingosine 1-phosphate receptor modular, ameliorates experimental autoimmune encephalomyelitis by inhibition of T cell infiltration. It is the active metabolite of FTY720-phosphate.

Solubility:
DMSO, Methanol (Sparingly)

Method for Determining Identity:
Proton NMR Spectroscopic Analysis

Purity:
~98%. 78.4% ee by HPLC

Melting Point:
>190C

TLC Conditions:
SiO2; Dichloromethane: Methanol: Acetic acid; 4: 1: 1; Visualized with AMCS; Single spot Rf=0.4.

Storage and Stability:
May be stored at RT for short-term only. Long-term storage is recommended at -20C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Toxicity and Hazards:
Due to the potential danger associated with the use of some of United States Biological biochemicals, all products should be handled by qualified personnel only, trained in laboratory procedures, and familiar with potential hazards. Information is not available on the possible hazards of many experimental compounds. The absence of a warning must not be interpreted as indication of safety. The ultimate responsibility for the proper handling of any and all chemicals lies with the user. All goods sold by United States Biological carry the condition that liability for any injury, loss or damage whatsoever to persons or real property resulting from the handling of the said goods lies with the user. Acceptance of our goods binds the customer to these terms.

CAS Number:
402616-26-6

Molecular Formula:
C19H34NO5P

Molecular Weight:
387.45
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. Toxicity and Hazards:All products should be handled by qualified personnel only, trained in laboratory procedures.
1. Chiba, K., et al.: J. Immunol., 160, 5037 (1998), 2. Brinkmann, V., et al.: J. Biol. Chem., 277, 21453 (2002), 3. Kiuchi, M., et al.: Bioorganic & Medicinal Chemistry, 13, 425 (2005)

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.