Technical Data
F9103-50E
FTO (Fatso, Fat Mass and Obesity-associated Protein, Protein Fatso)
Description:
Variants in the FTO (fat mass and obesity associated) gene, encoding for protein, fatso, are associated with increased body mass index and obesity in humans. The precise function of this protein remains to be determined. There are four isoforms produced by alternative splicing (FASTA: FTO isoform 1, 2, 3, and 4).

Applications:
Suitable for use in ELISA and Western Blot. Other applications not tested.

Recommended Dilution:
ELISA: 1:128,000
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
100ug-20CBlue IceHumanGoat
Concentration:
~0.5mg/ml
Immunogen:
Synthetic peptide corresponding to QQKPDCRPYWEKDD from the Internal region of FTO (NP_036066.2).
Purity:
Purified by affinity chromatography.
Form
Supplied as a liquid in Tris saline, 0.02% sodium azide, pH7.3, 0.5% BSA.
Specificity:
Recognizes FTO. Species Sequence Homology: human, rat, canine, porcine.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Gerken T, Girard CA, Tung YC, Webby CJ, Saudek V, Hewitson KS, Yeo GS, McDonough MA, Cunliffe S, McNeill LA, Galvanovskis J, Rorsman P, Robins P, Prieur X, Coll AP, Ma M, Jovanovic Z, Farooqi IS, Sedgwick B, Barroso I, Lindahl T, Ponting CP, Ashcroft FM, O'Rahilly S, Schofield CJ. The obesity-associated FTO gene encodes a 2-oxoglutarate-dependent nucleic acid demethylase. Science. 2007 Nov 30;318(5855):1469-72. Epub 2007 Nov 8. PMID: 17991826.