Technical Data
FUSIP1 (FUS-interacting Protein (Serine-arginine Rich) 1, FUS Interacting Serine Arginine Rich Protein 1, 40kD SR-repressor Protein, FUSIP2, NSSR, OTTHUMP00000015774, Serine Arginine Repressor Protein 40kD, SFRS13, Splicing Factor SRp38, SRp38, SRp40, TLS
FUSIP1 is a member of the serine-arginine (SR) family of proteins, which is involved in constitutive and regulated RNA splicing. Members of this family are characterized by N-terminal RNP1 and RNP2 motifs, which are required for binding to RNA, and multiple C-terminal SR/RS repeats, which are important in mediating association with other cellular proteins. FUSIP1 can influence splice site selection of adenovirus E1A pre-mRNA. It interacts with the oncoprotein TLS, and abrogates the influence of TLS on E1A pre-mRNA splicing. Alternative splicing of this gene results in at least two transcript variants encoding different isoforms. This antibody is specific for isoform 3 of FUSIP1.

Suitable for use Western Blot. Other applications not tested.

Recommended Dilution:
Western Blot: 0.5 mg/ml,
Optimal dilutions to be determined by the researcher.

Positve Control:
HepG2 whole cell extracts. ~22kDa

Storage and Stability:
May be stored at 4C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20C. Aliquots are stable for at least 3 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
PabIgGAffinity Purified
100ul-20CBlue IceHumanRabbit
Not determined
Synthetic peptide corresponding to an internal portion of the human protein (within residues 100-200). [O75494]
Purified by immunoaffinity chromatography.
Supplied as a liquid in Tris-citrate/phosphate, pH 7-8, 0.01% sodium azide.
Recognizes human FUSIP1. Species sequence homology: 100% to mouse FUSIP1 isoform 3.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.