Technical Data
F9510
Fumitremorgin C
250ug
Biochemicals Storage: -20CShipping: Blue Ice
Fumitremorgin C is a tremorgenic mycotoxin isolated from Aspergillus fumigatus. Recent research has recognized Fumitremorgin C as a potent and specific inhibitor of the breast cancer resistance protein (BCRP/ABCG2) multidrug transporter. It reverses multidrug resistance mediated by BCRP and increases cytotoxicity of several anticancer agents in vitro.

Solubility:
Soluble in ethanol, methanol, DMF or DMSO.

Storage and Stability:
Lyophilized powder may be stored at -20C. Stable for 12 months at -20C. Reconstitute with ethanol, methanol, DMF or DMSO. Aliquot to avoid repeated freezing and thawing. Store at -20C. Reconstituted product is stable for 6 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

CAS Number:
118974-02-0

Molecular Formula:
C22H25N3O3

Molecular Weight:
379.5
Source: Aspergillus fumigatus MST-FP1831
Purity: 95% by HPLC
Form: Supplied as an off-white lyophilized powder.

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
1. Allen, J.D., et al., Mol. Cancer Ther. 1: 417 (2002). 2. Rabindran, S.K., et al., Cancer Res. 60: 47 (2000). 3. Cui, C.B., et al., J. Antibiot. 49: 527 (1996). 4. Cole, R.J., et al., J. Agric. Food Chem. 25: 826 (1977).

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.