Technical Data
F9510
Fumitremorgin C
250ug
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Technical Data |
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F9510 |
Fumitremorgin C |
250ug |
| Biochemicals | Storage: -20°CShipping: Blue Ice |
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Fumitremorgin C is a tremorgenic mycotoxin isolated from Aspergillus fumigatus. Recent research has recognized Fumitremorgin C as a potent and specific inhibitor of the breast cancer resistance protein (BCRP/ABCG2) multidrug transporter. It reverses multidrug resistance mediated by BCRP and increases cytotoxicity of several anticancer agents in vitro. Solubility: Soluble in ethanol, methanol, DMF or DMSO. Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with ethanol, methanol, DMF or DMSO. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. CAS Number: 118974-02-0 Molecular Formula: C22H25N3O3 Molecular Weight: 379.5 |
Source: Aspergillus fumigatus MST-FP1831 Purity: 95% by HPLC Form: Supplied as an off-white lyophilized powder. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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1. Allen, J.D., et al., Mol. Cancer Ther. 1: 417 (2002). 2. Rabindran, S.K., et al., Cancer Res. 60: 47 (2000). 3. Cui, C.B., et al., J. Antibiot. 49: 527 (1996). 4. Cole, R.J., et al., J. Agric. Food Chem. 25: 826 (1977).
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