Technical Data
G1044-47C
Galectin-1, Recombinant, Human (GAL1, LGALS1, GAL-1, Lectin galactoside-binding soluble 1, Beta-galactoside- binding lectin L-14-I, Lactose-binding lectin 1, S-Lac lectin 1, Galaptin, 14kD lectin, HPL, HBL, Putative MAPK-activating protein PM12, GBP, DKFZ
10ug
50ug
Molecular Biology Storage: -70CShipping: Blue Ice
Human Galectin-1 belongs to a large family of carbohydrate-binding proteins that contain structural similarities in there carboyhydrate recognition domains. Galectin-1, also known as L-14, BHL or galaptin, can be either monomeric or homodimeric, and is found in a wide varity of cells and tissue types. Galectin-1 controls cell growth and proliferation and induces apoptosis of activated T cells. It can also modulate cytokine secretion or inhibit pro-inflammatory cytokine production. Galectin-1 plays an important role in acute and chronic inflammation. Galectin-1 is comprised of 134 amino acids with a molecular weight of 14.5kD.

Endotoxin: <0.01ng/ug or <0.1EU/ug as per LAL

Biological Activity: Human Galectin-1 is a chemoattract for human blood monocytes. ED 50 range is from 0.05 3.0ug/ml.

AA Sequence:
ACGLVASNLN LKPGECLRVR GEVAPDAKSF VLNLGKDSNN LCLHFNPRFN AHGDANTIVC NSKDGGAWGT EQREAVFPFQ PGSVAEVCIT FDQANLTVKL PDGYEFKFPN RLNLEAINYM AADGDFKIKC VAFD

Storage and Stability:
Lyophilized powder may be stored at -20C. Stable for 12 months at -20C. Reconstitute with sterile ddH2O, aliquot and store at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Molecular Weight:
14.5 kD
Source: Recombinant, human, E. coli
Purity: 95% as determined by reducing and non-reducing SDS-PAGE.

Form: Supplied as a lyophilized powder. Reconstitute with sterile dH2O PBS to 0.1-1mg/ml, which can be further diluted into other aqueous solutions.

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
General References:
1. Camby, I. et al. (2006) Galectin1: A small protein with major functions., Glycobiol. 16: 137R157R.
2 Hellstern, S., et al., J. Biol. Chem. 277(18): 15,690-15,696 (2002).

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.