Technical Data
G2005-02
Ganglioside GD2 (Disialoganglioside GD2)
Description:
GD2 has been identified as tumor-associated antigens expressed on the surface of neuroectoderm-derived tumors
(melanoma, neuroblastoma and glioma) and T-cell leukemia. Gangliosides (sialic acid-containing glycosphingolipids) are normal membrane constituents and highly expressed in the vertebral central nervous system.

Applications:
Suitable for use in Immunofluorescence, Flow Cytometry, Immunohistochemistry, Immunocytochemistry and Cytotoxicity. Other applications not tested.

Recommended Dilutions:
Flow Cytometry: 1-2ug per 10e6 cells
Immunohistochemistry: Frozen tissue sections
Immunofluorescence: Cells in culture
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
MabIgG2a2Q549Affinity Purified
SizeStorageShippingSourceHost
100ug-20CBlue IceHumanMouse
Concentration:
~1mg/ml
Immunogen:
Human neuroblastoma cell line
Purity:
Purified by Protein A affinity chromotography.
Form
Supplied as a liquid in PBS, pH 7.6, 0.1% sodium azide.
Specificity:
Recognizes human GD2 ganglioside.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Cheresh, D.A. et al. (1986) Cancer Res. 46: 51125118. 2. Mujoo, K. et al. (1987) Cancer Res. 47: 10981104. 3. Mujoo, K. et al. (1989) Cancer Res. 49: 28572861.