Technical Data
Gastric Inhibitory Polypeptide (GIP)
Human gastric inhibitory polypeptide (GIP) is a 42aa peptide belonging to the glucagon-secretin family of peptide hormones. It is secreted by endocrine cells in the duodenal mucosa and stimulates glucose-dependent insulin secretion as well as GLP-1 release from more distal endocrine (L) cells in the intestinal mucosa. GIP shows amino-acid sequence similarities to glucagon, GLP-1 and GLP-2 (from ~50% identity for glucagon to 30% identity for GLP-2).

Suitable for use in ELISA and Immunohistochemistry. Other applications not tested.

Recommended Dilutions:
ELISA: 1:2000 coated directly at 2ug/ml. G2019F binds free GIP in solution.
Optimal dilutions to be determined by the researcher.

Sp2/mIL-6 myeloma cells with spleen cells from NMRI x Balb/c mice.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
MabIgG1,k6F106Affinity Purified
100ul-20CBlue IceHumanMouse
Synthetic human gastric inhibitory polypeptide
Purified by Protein A affinity chromatography.
Supplied as a liquid in PBS, pH 7.4, 15mM sodium azide. Also available without azide. See G2019F1.
Recognizes human Gastric Inhibitory Polypeptide (GIP). Binds free GIP in solution. Crossreacts up to 10% with PACAP and human GLP-2. <0.1% crossreactivity with glucagon, GLP-1 and VIP.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.