Technical Data
G2033-03
GFR alpha1, IN (GDNFRa, Glial Cell-derived Neurotrophic Factor Receptor a1, RETL1, Ret ligand 1, TGFb-related Neurotrophic Factor Receptor 1, TrnR1, Glycosylphosphadidylinositol linked Protein)
Description:
Applications:
Suitable for use in Western Blot and Immunohistochemistry. Other applications have not been tested.

Recommended Dilution:
Western Blot: 1:500-1:1000
Immunohistochemistry: paraffin; requires antigen retrieval with sodium citrate buffer, pH 6.0.
Optimal working dilutions to be determined by researcher.

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.


TypeIsotypeCloneGrade
PabIgGHighly Purified
SizeStorageShippingSourceHost
100ug-20°CBlue IceHumanRabbit
Concentration:
~0.5mg/ml
Immunogen:
Peptide from C terminus of human GDNFR alpha.
Purity:
Purified IgG prepared by ion exchange chromatography.
Form
Supplied as a liquid in PBS with 0.02% sodium azide.
Specificity:
Recognizes GDNFR alpha, a cell surface receptor for glial cell derived neutrophic factor (GDNF).GDNFR alpha has more recently been designated GFR alpha -1. Species Crossreactivity: Human, mouse, rat
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Jing, S. et al. (1996) GDNF-induced activation of the Ret protein tyrosine kinase is mediated by GDNFR-alpha, a novel receptor for GDNF. Cell 85: 1113-1124. 2. Treanor, J.J.S. et al. (1996). Characterization of a multicomponent receptor for GDNF. Nature 382: 80-83. 3. (1997) Nomenclature of GPI­linked receptors for the GDNF ligand family. GFR(alpha) Nomenclature Committee. Neuron 19: 485.