		Technical Data
G2033-03	GFR alpha1, IN (GDNFRa, Glial Cell-derived Neurotrophic Factor Receptor a1, RETL1, Ret ligand 1, TGFb-related Neurotrophic Factor Receptor 1, TrnR1, Glycosylphosphadidylinositol linked Protein)

Description:
Applications:
Suitable for use in Western Blot and Immunohistochemistry. Other applications have not been tested.

Recommended Dilution:
Western Blot: 1:500-1:1000
Immunohistochemistry: paraffin; requires antigen retrieval with sodium citrate buffer, pH 6.0.
Optimal working dilutions to be determined by researcher.

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Type	Isotype	Clone	Grade
Pab	IgG		Highly Purified

Size		Storage	Shipping	Source	Host
100ug		-20°C	Blue Ice	Human	Rabbit

Concentration:

~0.5mg/ml

Immunogen:

Peptide from C terminus of human GDNFR alpha.

Purity:

Purified IgG prepared by ion exchange chromatography.

Form

Supplied as a liquid in PBS with 0.02% sodium azide.

Specificity:

Recognizes GDNFR alpha, a cell surface receptor for glial cell derived neutrophic factor (GDNF).GDNFR alpha has more recently been designated GFR alpha -1. Species Crossreactivity: Human, mouse, rat

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

1. Jing, S. et al. (1996) GDNF-induced activation of the Ret protein tyrosine kinase is mediated by GDNFR-alpha, a novel receptor for GDNF. Cell 85: 1113-1124. 2. Treanor, J.J.S. et al. (1996). Characterization of a multicomponent receptor for GDNF. Nature 382: 80-83. 3. (1997) Nomenclature of GPIlinked receptors for the GDNF ligand family. GFR(alpha) Nomenclature Committee. Neuron 19: 485.