Technical Data
G2036-18
Glial Derived Neurotrophic Factor, Recombinant, Human (GDNF)
50ug
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Technical Data |
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G2036-18 |
Glial Derived Neurotrophic Factor, Recombinant, Human (GDNF) |
50ug |
| Growth Factors, Cytokines | Storage: -20°CShipping: Blue Ice |
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Human GDNF (Glial-Derived Neurotrophic Factor) is a 30.1kD protein that specifically promotes dopamine uptake and survival of midbrain neurons. GDNF is a disulphide-linked homodimer, formed by two identical 134aa subunits. Source: Recombinant corresponding to human GDNF expressed in E. coli. Biological Activity: The ED50 as determined by the dose-dependent dopamine uptake by rat ventral mesencephalic cultures was found to be in the range of 4-8ng/ml. Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. Molecular Weight: ~30.1kD |
Source: E.coli Purity: ~98% (SDS-PAGE and HPLC). Endotoxin: <0.1EU/ug Concentration: Not determined Form: Supplied as a lyophilized powder from 10mM sodium citrate, 150mM sodium chloride, pH 4. Reconstitute in sterile ddH2O to 0.1-1.0mg/ml. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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