Technical Data
G3990
L-Glutamate (L-Glutamic Acid), Conjugated
Description:
Glutamate is the main excitatory neurotransmitter in the brain. To date five glutamate transporters have been cloned: GLAST (EAAT1), GLT1 (EAAT2), EAAC1 (EAAT3), EAAT4, and EAAT5. These transporters are believed to be critical in reducing potentially toxic extracellular concentration of glutamate by rapid uptake into nerve terminals and glial cells.

Applications:
Suitable for use in ELISA and Immunohistochemistry. Other applications not tested.

Recommended Dilutions:
Immunohistochemistry: 1:1000-1:5000
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
MabIgM,k2MG3Purified
SizeStorageShippingSourceHost
50ug-20CBlue IceMouse
Concentration:
~1mg/ml
Immunogen:
Synthetic L-Glutamate labeled with a protein carrier
Purity:
Purified by ammonium sulfate precipitation
Form
Supplied as a liquid. No preservatives added.
Specificity:
Recognizes protein-linked Glutamate. Crossreactivity: L-Glutamate-G-(Pc) 1:1, D-Glutamate-G-(Pc) 1:100, L-Asparate-G-(Pc) 1:50,000, GABA-G-(Pc) 1:50,000. (G=Glutaraldehyde, GAMA=Gamma Aminobutyric acid)
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
Chagnauld J.L., Campistron G. and Geffard M. Monoclonal antibody directed against glutaraldehyde conjugated glutamate and immunocytochemical applications in the rat brain. Brain Res., (1989), 481, 175-181.