		Technical Data
G3990	L-Glutamate (L-Glutamic Acid), Conjugated

Description:
Glutamate is the main excitatory neurotransmitter in the brain. To date five glutamate transporters have been cloned: GLAST (EAAT1), GLT1 (EAAT2), EAAC1 (EAAT3), EAAT4, and EAAT5. These transporters are believed to be critical in reducing potentially toxic extracellular concentration of glutamate by rapid uptake into nerve terminals and glial cells.

Applications:
Suitable for use in ELISA and Immunohistochemistry. Other applications not tested.

Recommended Dilutions:
Immunohistochemistry: 1:1000-1:5000
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Type	Isotype	Clone	Grade
Mab	IgM,k	2MG3	Purified

Size		Storage	Shipping	Source	Host
50ug		-20°C	Blue Ice		Mouse

Concentration:

~1mg/ml

Immunogen:

Synthetic L-Glutamate labeled with a protein carrier

Purity:

Purified by ammonium sulfate precipitation

Form

Supplied as a liquid. No preservatives added.

Specificity:

Recognizes protein-linked Glutamate. Crossreactivity: L-Glutamate-G-(Pc) 1:1, D-Glutamate-G-(Pc) 1:100, L-Asparate-G-(Pc) 1:50,000, GABA-G-(Pc) 1:50,000. (G=Glutaraldehyde, GAMA=Gamma Aminobutyric acid)

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

Chagnauld J.L., Campistron G. and Geffard M. Monoclonal antibody directed against glutaraldehyde conjugated glutamate and immunocytochemical applications in the rat brain. Brain Res., (1989), 481, 175-181.