Technical Data
G8127-12C
Glutathione Peroxidase 2 (GPX2, GPx-2, GSHPx-2, Gastrointestinal Glutathione Peroxidase, Glutathione Peroxidase-gastrointestinal, GPx-GI, GSHPx-GI, Glutathione Peroxidase-related Protein 2, GPRP-2)
Description:
Glutathione peroxidase 2 (GPX2), an extracellular, selenium-dependent, gastrointestinal anti-oxidant enzyme, and member of the glutathione peroxidase family, which plays a major role in glutathione-dependent hydrogen peroxide-reducing activity, in gastrointestinal tract epithelium.

Applications:
Suitable for use in ELISA, Immunohistochemistry and Western Blot. Other applications not tested.

Recommended Dilution:
Western Blot: 1-3ug/ml
ELISA: >1:4000
Immunohistochemistry: Paraffin
Optimal dilutions to be determined by the researcher.

Positive Control:
Human Prostate lysate

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
100ug-20CBlue IceHumanGoat
Concentration:
~0.5mg/ml
Immunogen:
Synthetic peptide corresponding to C-SLDGEKVDFN, from the internal region of the protein sequence according to NP_002074.2.
Purity:
Purified by immunoaffinity chromatography.
Form
Supplied as a liquid in Tris saline, 0.02% sodium azide, pH7.3, 0.5% BSA.
Specificity:
Recognizes GPX2. Species Crossreactivity: rat and human. Species sequence homology: canine, mouse.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Esworthy RS, Yang L, Frankel PH, Chu FF. Epithelium-specific glutathione peroxidase, Gpx2, is involved in the prevention of intestinal inflammation in selenium-deficient mice. J Nutr. 2005 Apr;135(4):740-5. PMID: 15795427.