Technical Data
G8235-52G
GPC4, ID (Glypican-4, K-glypican, Secreted Glypican-4, UNQ474/PRO937)
Description:
Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The GPC4 gene is adjacent to the 3' end of GPC3 and may also play a role in Simpson-Golabi-Behmel syndrome.

Applications:
Suitable for use in ELISA and Western Blot. Other applications not tested.

Recommended Dilution:
ELISA: 1:1,000
Western Blot: 1:50-1:100
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGPurified
SizeStorageShippingSourceHost
100ug-20°CBlue IceHumanRabbit
Concentration:
~0.25mg/ml
Immunogen:
Synthetic peptide selected from the Center region of human GPC4 (KLH).
Purity:
Purified by ammonium sulfate precipitation.
Form
Supplied as a liquid in PBS, 0.09% sodium azide.
Specificity:
Recognizes human GPC4.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1.Karumanchi,S.A., Mol. Cell 7(4), 811-822 (2001). 2.Hagihara,K., Dev. Dyn. 219(3), 353-367 (2000). 3.Veugelers,M., Hum. Mol. Genet. 9(9), 1321-1328 (2000). 4.Veugelers,M., Genomics 53(1), 1-11 (1998).