Technical Data
G8581-11
Gpihbp1 (GPI-anchored HDL-binding protein 1, GPI-anchored High-Density Lipid-binding protein 1, GlycosylPhosphatidylInositol-anchored high-density lipoprotein-binding protein 1)
Description:
GPI-anchored HDL-binding protein 1 (Gpihbp1) is a novel protein that may be involved in the regulation of the delivery of fats to cells for energy and storage. Digested fats travel to the small intestine, where they are packaged into chylomicrons (particles filled with triglycerides). Chylomicrons then travel through the bloodstream and deliver triglycerides to tissues that are hungry for fuel or to adipose tissue for energy storage. Triglycerides are broken down or hydrolyzed by the enzyme lipoprotein lipase (LpL). The triglyceride breakdown products are then taken up and used by cells. Gpihbp1 is the molecule in capillaries that facilitates the capture of chylomicrons and facilitates the interaction with LpL. It has been shown that fats in the bloodstream are not readily metabolized in the absence of GPIHBP1.

Positive Control: Mouse kidney lysate

Applications:
Suitable for use in Western Blot. Other applications not tested.

Recommended Dilution:
Optimal dilutions to be determined by the researcher.

Storage and Stability:

May be stored at 4C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20C. Aliquots are stable for at least 12 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
TypeIsotypeCloneGrade
PabAffinity Purified
SizeStorageShippingSourceHost
100ul-20CBlue IceMouseRabbit
Concentration:
~0.9mg/ml
Immunogen:
A synthetic peptide within an internal region [residues 100-200] of the mouse GPI-anchored HDL-binding protein 1 protein. [Swiss-Prot# Q9D1N2]. Homology: 100% with mouse.
Purity:
Purified by immunoaffinity chromatography.
Form
Supplied as a liquid in Tris-glycine, 150mM sodium chloride, pH 7.2.
Specificity:
Species Crossreactivity: This antibody reacts with mouse protein. Other species have not been tested.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Beigneux, AP, et al. Cell Metabolism. 5(4): 279-291 (2007)