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Technical Data |
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G8975-20 |
GRO/KC, Recombinant, Rat (Cxcl1, Chemokine (C-X-C Motif) Ligand 1 (Melanoma Growth Stimulating Activity, alpha), Cinc1, CINC-1, C-X-C Motif Chemokine 1, Cytokine-induced Neutrophil Chemoattractant 1, Gro1, Growth-regulated alpha Protein, Platelet-derived |
5ug 25ug |
| Growth Factors, Cytokines | Storage: -20°CShipping: RT |
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All three isoforms of GRO are CXC chemokines that can signal through the CXCR1 or CXCR2 receptors. The GRO proteins chemoattract and activate neutrophils and basophils. Recombinant rat GRO/KC is a 7.8kD protein consisting of 72 amino acids including the 'ELR' motif common to the CXC chemokine family that bind to CXCR1 or CXCR2. Endotoxin: 0.1ng/ug Biological Activity: Determined by ability to chemoattract total rat neutrophils at a concentration range of 10-100ng/ml. Responding Cells (partial list): Neutrophils Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute by adding sterile water, aliquot and store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. Molecular Weight: 7.8kD |
Source: E. coli Purity: 98% by SDS-PAGE and HPLC Form: Supplied as a lyophilized powder. No additives. Reconstitute in sterile dH2O to 0.1-1mg/ml. This solution can then be diluted into other aqueous buffers. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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