Technical Data
H1827-45
HCST (Hematopoietic Cell Signal Transducer, DNAX Activation Protein 10, DAP10, KAP10, PIK3AP, Phosphoinositide-3-kinase Adaptor Protein, Transmembrane Adapter Protein KAP10)
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Technical Data |
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H1827-45 |
HCST (Hematopoietic Cell Signal Transducer, DNAX Activation Protein 10, DAP10, KAP10, PIK3AP, Phosphoinositide-3-kinase Adaptor Protein, Transmembrane Adapter Protein KAP10) |
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Description: This gene encodes a transmembrane signaling adaptor that contains a YxxM motif in its cytoplasmic domain. The encoded protein may form part of the immune recognition receptor complex with the C-type lectin-like receptor NKG2D. As part of this receptor complex, this protein may activate phosphatidylinositol 3-kinase dependent signaling pathways through its intracytoplasmic YxxM motif. This receptor complex may have a role in cell survival and proliferation by activation of NK and T cell responses. Alternative splicing results in two transcript variants encoding different isoforms. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. |
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