Technical Data
H1827-53K
HDAC2 (Histone Deacetylase 2, Tanscriptional Regulator Homolog RPD3, HD2)
Description:
Histone deacetylase 2 (HDAC2), or transcriptional regulator homolog RPD3 L1, is highly homologous to the yeast transcription factor RPD3 (reduced potassium dependency 3) gene. As in yeast, human HDA2 is likely to be involved in regulating chromatin structure during transcription. It has been implicated to associate with YY1, a mammalian zinc-finger transcription factor, which negatively regulates transcription by tethering RPD3 to DNA as a cofactor. This process is highly concerved from yeast to human.

Applications:
Suitable for use in Western Blot and Immunoprecipitation. Other applications not tested.

Recommended Dilution:
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20C. Aliquots are stable for at least 12 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
TypeIsotypeCloneGrade
PabAffinity Purified
SizeStorageShippingSourceHost
100ug-20CBlue IceHumanRabbit
Concentration:
~1mg/ml
Immunogen:
The epitope recognized maps to the N-terminus of human Histone Deacetylase 2 using the numbering given in entry NP_001518.1 (GeneID 3066).
Purity:
Purified by immunoaffinity chromatography.
Form
Tris-citrate/phosphate buffer, pH 7 to 8
Specificity:
This antibody is specific to the human HDAC2 protein.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.