Technical Data
H1830-94N
Heat Shock Protein 70 (HSP70)
Description:
Heat shock proteins, HSPs or stress response proteins SRPs, are synthesized in a variety of environmental and patholphysiological stressful conditions. Many HSPs are involved in processes such as protein denaturation-renaturation, folding-unfolding, transport-translocation, activation-inactivation, and secretion. HSP70 is found to be associated with steroid receptors, actin, p53, polyoma T antigen, nucleotides, and other unknown proteins. Also, HSP70 has been shown to be involved in protective roles against thermal stress, cytotoxic drugs, and other damaging conditions.

Applications:
Suitable for use in Immunohistochemistry. Other applications not tested.

Recommended Dilution:
Immunohistochemistry (Paraffin/frozen): 1:75-1:250 in an ABC all method. Incubate for 30 minutes at RT.
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGSerum
SizeStorageShippingSourceHost
250ul-20CBlue IceHumanRabbit
Concentration:
Not Determined
Immunogen:
Purified heat shock protein (Dnak) from E. coli. Cellular Localization: Cytoplasmic, nuclear.
Purity:
Serum
Form
Supplied as a liquid, sodium azide.
Specificity:
Recognizes the two major human HSP 70s (HSP 72 and HSP 73). Stains epithelial cells in many different tissues (e.g. tonsil, stomach, small and large intestine, bile ducts, ovary and prostate).
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.