Technical Data
Hedgehog (Hh) Signaling Pathway Antagonist (N-[4-Chloro-3-(trifluoromethyl)phenyl]-N-[[3-(4-fluorophenyl)-3,4-dihydro-4-oxo-2-quinazolinyl]methyl-urea)
Biochemicals Storage: 4CShipping: Blue Ice
Cell-permeable. A potent antagonist of the Hedgehog (Hh) signaling pathway (IC50 = 70nM).

Storage and Stability:
Lyophilized powder may be stored at 4C. Stable for 12 months at 4C. Reconstitute with sterile DMSO. Aliquot to avoid repeated freezing and thawing. Store at 4C. Reconstituted product is stable for 6 months at 4C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

CAS Number:

Molecular Formula:
Purity: ~97% (HPLC)
Form: Supplied as a white to off-white powder. Reconstitute with DMSO.

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
1. Brunton, S.A., et al. (2008). J. Med. Chem. 51, 1108.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.