Technical Data
H1835-60
Hedgehog (Hh) Signaling Pathway Antagonist (N-[4-Chloro-3-(trifluoromethyl)phenyl]-N’-[[3-(4-fluorophenyl)-3,4-dihydro-4-oxo-2-quinazolinyl]methyl-urea)
1mg
|
Technical Data |
|
H1835-60 |
Hedgehog (Hh) Signaling Pathway Antagonist (N-[4-Chloro-3-(trifluoromethyl)phenyl]-N’-[[3-(4-fluorophenyl)-3,4-dihydro-4-oxo-2-quinazolinyl]methyl-urea) |
1mg |
| Biochemicals | Storage: 4°CShipping: Blue Ice |
|
Cell-permeable. A potent antagonist of the Hedgehog (Hh) signaling pathway (IC50 = 70nM). Storage and Stability: Lyophilized powder may be stored at 4°C. Stable for 12 months at 4°C. Reconstitute with sterile DMSO. Aliquot to avoid repeated freezing and thawing. Store at 4°C. Reconstituted product is stable for 6 months at 4°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. CAS Number: 330796-24-2 Molecular Formula: C23H15ClF4N4O2 |
Purity: ~97% (HPLC) Form: Supplied as a white to off-white powder. Reconstitute with DMSO. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
|
1. Brunton, S.A., et al. (2008). J. Med. Chem. 51, 1108.
|
||