Technical Data
Heterochromatin Protein p25, CT (p25beta, HP1Hsbeta, CBX1, M31, Modifier 1 Protein, Heterochromatin Protein 1 Homolog beta, HP1 beta, Chromobox Protein Homolog 1, CBX)
CBX1 is a highly conserved nonhistone protein, which is a member of the heterochromatin protein family . The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The protein may play an important role in the epigenetic control of chromatin structure and gene expression.

Suitable for use in ELISA and Western Blot. Other applications not tested.

Recommended Dilution:
ELISA: 1:1,000
Western Blot: 1:100-1:500
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
PabIgGAffinity Purified
200ul-20CBlue IceHumanRabbit
As reported
Synthetic peptide selected from the C-terminal region of human CBX1 (KLH).
Purified by immunoaffinity chromatography.
Supplied as a liquid in PBS, 0.09% sodium azide.
Recognizes human CBX1.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Aagaard,L.,, EMBO J. 18(7), 1923-1938 (1999).