		Technical Data
H6001-13	HIV-1 (Human Immunodeficiency Virus Type 1) (HRP)

Description:
HIV is a member of the genus Lentivirus, part of the family of Retroviridae, which use reverse transcriptase to convert the viral RNA genome into double stranded DNA. This is then integrated into the cell’s DNA, which is followed by latency or active HIV replication. HIV primarily infects CD4+ T lymphocytes, resulting in their dramatic decline. When CD4+ T cell numbers decline below a critical level, cell-mediated immunity is lost, and the body becomes progressively more susceptible to opportunistic infections. If untreated, this can lead to AIDS (Acquired Immunodeficiency Syndrome).

Applications:
Suitable for Immunocyochemistry, Western Blot and ELISA.
Other applications have not been tested.

Recommended Dilutions:
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Conjugated to horseradish peroxidase (HRP). Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates.

Type	Isotype	Clone	Grade
Pab	IgG		Purified

Size		Storage	Shipping	Source	Host
1ml		-20°C	Blue Ice		Goat

Concentration:

1-2 mg/ml

Immunogen:

Human isolate confirmed

Purity:

Purified

Form

Supplied as a liquid in PBS, 10mg/ml BSA, 0.002% thimerosal. Labeled with Horseradish Peroxidase (HRP).

Specificity:

Recognizes purified virions, disrupted. Reacts with the whole virus and all the major viral proteins including p17, p24, gp41, p53, p64, gp120 and gp160. Does not react with T4+ human lymphocytes.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.