Technical Data
H6098-07L
HLA Class 1 Antigen A2 (HLA Class I Histocompatibility Antigen, A-2 alpha Chain, MHC Class I Antigen A*2, HLA-A, HLAA)
Description:
Human leukocyte antigen (HLA) A2 is a subset of MHC-class I molecules encoded by A*02 alleles. HLA-A2 is more common in Northern Asia and North America populations. MHC class I antigens associated with B2-microglobulin are expressed by all human nucleated cells. MHC class I molecules are involved in presentation of antigens to CD8+ T cells playing an important role in cell-mediated immune responses and tumor surveillance.

Applications:
Suitable for use in Flow Cytometry. Other applications not tested.

Recommended Dilution:
Flow Cytometry: 2ug/10e5 cells in 100ul
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
MabIgG2b,kBB7.2Affinity Purified
SizeStorageShippingSourceHost
100ug-20CBlue IceHumanMouse
Concentration:
~0.5mg/ml
Immunogen:
Papain solubilized HLA-A2
Purity:
Purified by immunoaffinity chromatography.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Specificity:
Recognizes human HLA-A2.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Brodsky, F., et al. 1979. Immunol. Rev. 47:3. 2. Parham, P. and FM. Brodsky., et al. 1981. Hum. Immunol. 3:277.