Technical Data
H6285-25D
HNRPK (Heterogeneous Nuclear Ribonucleoprotein K, Transformation Up-regulated Nuclear Protein, hnRNP K, TUNP, HNRNPK)
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Technical Data |
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H6285-25D |
HNRPK (Heterogeneous Nuclear Ribonucleoprotein K, Transformation Up-regulated Nuclear Protein, hnRNP K, TUNP, HNRNPK) |
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Description: hnRNP K (Heterogeneous nuclear ribonucleoprotein K) is a pre-mRNA binding protein and a component of hnRNP complexes providing substrate for pre-mRNA processing before becoming translatable mRNAs in cytoplasm. This protein containing KH domains and is ubiquitously expressed in the cytoplasm and the nucleus with a predicted molecular weight approximately 51kD. hnRNP K expression and function are increased by epidermal growth factor (EGF). hnRNP K acts as transcriptional regulator and functions in nucleocytoplasmic shuttling, and is modified by phosphorylation (PKC delta, c-Src) and acetylation. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. |
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