Technical Data
H7024-26A
HOXD13 (Homeobox Protein Hox-D13, Homeobox Protein Hox-4I, HOX4I)
Description:
HOXD13 (homeobox protein D13) belongs to a class of transcription factors called homeobox proteins. In vertebrates, homeobox are found in clusters called A, B, C, and D on four separate chromosomes. Expression of homeobox proteins is spatially and temporally regulated during embryonic development. The gene encoding HOXD13 is part of the D cluster on chromosome 2. Deletions that remove the entire HOXD gene cluster or the 5' end of this cluster have been associated with severe limb and genital abnormalities. Mutations in the HOXD13 gene cause synpolydactyly.

Applications:
Suitable for use in ELISA. Other applications not tested.

Recommended Dilution:
ELISA: 1:8000
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabAffinity Purified
SizeStorageShippingSourceHost
100ug-20CBlue IceHumanGoat
Concentration:
~0.5mg/ml
Immunogen:
Synthetic peptide corresponding to C-KSSFPGDVALNQPD, from HOXD13, at the internal region of the protein (NP_000514.2).
Purity:
Purified by immunoaffinity chromatography.
Form
Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
Specificity:
Recognizes HOXD13. Species sequence homology: Bovine, human, mouse and rat.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Cantile M, Franco R, Tschan A, Baumhoer D, Zlobec I, Schiavo G, Forte I, Bihl M, Liguori G, Botti G, Tornillo L, Karamitopoulou-Diamantis E, Terracciano L, Cillo C, HOX D13 expression across 79 tumor tissue types. Int J Cancer. 2009 Oct 1;125(7):1532-41.